1500
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Events
Europe's population was ~60 million. (''Jackson J. Spielvogel|Spielvogel'')
January 5 - Duke Ludovico Sforza recaptures Milan, but is soon driven out again by the French.
April 21 - Portugal | Portuguese navigator Pedro Álvares Cabral officially discovers Brazil and claims the land for Portugal.
November 11 - Treaty of Granada - Louis XII of France and Ferdinand II of Aragon agree to divide the Kingdom of Naples between them.
Emperor Go-Kashiwabara of Japan|Emperor Go-Kashiwabara ascends to the throne of Japan.
Battle of Hemmingstedt: The Denmark|Danish army fails to conquer the peasants' republic of Dithmarschen.
Battle of Lepanto (1500)|Second Battle of Lepanto - The Turkish fleet of Kemal Re'is defeats the Republic of Venice|Venetians. The Turks proceed to capture Modon, Lepanto, and Koron.
The Luo, a Nilotic people from modern Sudan, settle the Cwezi states, establishing the state of Buganda. (approximate date)
Diogo Dias is the first Europe|European to see Madagascar.
Births
February 22 - Cardinal Rodolfo Pio da Carpi, Italian humanist (d. 1564)
February 24 - Charles V, Holy Roman Emperor (died 1558)
April 12 - Joachim Camerarius, German classical scholar (died 1574)
April 23 - Alexander Ales, Scottish theologian (died 1565)
November 1 - Benvenuto Cellini, Italian goldsmith and sculptor (died 1571)
Johannes Aal, Swiss theologian and composer (died 1553)
John of Avila, Spanish mystic and saint (died 1569)
George Cavendish, English writer
Wu Cheng'en, Chinese novelist (died 1582)
Charles Dumoulin, French jurist (died 1566)
Heinrich Faber, German music theorist (died 1552)
Federico II of Gonzaga, Marquis of Mantua (died 1540)
Francisco de Moraes, Portuguese writer (died 1572)
Reginald Cardinal Pole, Archbishop of Canterbury (died 1558)
Mem de Sá, Governor-General of Brazil (died 1572)
Johann Stumpf, Swiss writer (died 1576)
Pietro Martire Vermigli, Italian theologian
Deaths
May 29 - Bartolomeu Dias, Portuguese explorer
June 19 - Edmund Tudor, Duke of Somerset (born 1499)
September 12 - Albert, Duke of Saxony (born 1443)
September 15 - John Morton, Archbishop of Canterbury
October 1 - John Alcock (bishop)|John Alcock, English churchman
October 21 - Emperor Go-Tsuchimikado of Japan (born 1442)
Juan Pérez de Gijón, Spanish composer (born 1460)
Feodor Kuritsyn, Russian statesman
Thomas Rotherham, English cleric and minister (born 1423)
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